In Matheson’s legendary tale, family man Scott Carey finds himself shrinking, slowly, day-by-day, inch-by-inch. While on vacation, he gets exposed to a radioactive cloud, the cause of this bizarre event. Scott once had an everyday existence as a husband and father, but now his shrinking shows no end in sight. He becomes a national spectacle, something worthy of newspaper headlines. As Carey shrinks smaller and smaller, his family become more and more unreachable giants, and the family cat becomes a predatory menace. In this world of disproportion, which grows more and more perilous with each passing day, Scott struggles to survive. He is pushed to the very limits of fear and existence.
As the story continues, Carey meets up with some circus performers and attempts to rebuild some semblance of a life. But since his shrinking never stops, all ideas of normal fade, and the threats never stop growing.